A week before Christmas, Kate Ryan moves back into her old neighborhood on the North side of Chicago. Back where she started and ended her P.I. business. Kate purchases a renovated brownstone and she gets it for a song. When Kate finds out that the former tenant, a scientist, was murdered in the kitchen, she understands why she got it so cheap.

Is it a coincidence the dead doctor worked at University Hospital with Maggie? When Kate accidentally discovers a journal from the murdered scientist in the brick wall of her fireplace, she realizes it is not.

All of the sudden, scientists are dropping like flies. Something very dark and dangerous is happening at University Hospital. Kate now fears for Maggie's safety all the while wondering who'll be dead for Christmas?