With the serum now in her bloodstream, Dr. Alex Taylor must find a suitable laboratory to continue her work to help the woman - well, vampire - she loves, Sebastian. Together they travel to Devon, England, where Sebastian hopes her old, old, friend, the flamboyant vamp Gaylen Prescott will assist them. All the while, they try to keep one step ahead of Nicholae, the elder in the hierarchy, who wants Sebastian destroyed. They find themselves deep in the catacombs of Guys Hospital in London and to Kendra, a sultry vamp who knew Sebastian quite well a century before, too well for Alex. Kendra is conducting similar experiments of her own. Alex becomes a reluctant comrade to this sexy vampire, and together they find a way for Sebastian and her world to survive the dawn.