A tawdry travelling medicine show is the last place you'd expect to find frontier scout Barnaby Skye and his two wives, But he's been hired to guide the caravan across the dangerous Sante Fe Trail. And when Skye starts a job, he follows through.

So when Indians abduct and ravish the troupe's beautiful young star, Skye has no choice but to kill her tormentors. Now, scores of vengeful Comanches gather to unleash their fury on Skye's party.

Surrounded and outnumbered, Skye and his women must defy the warriors' bloodlust, or face an agonizing death.