Refused a drink and threatened with violence in a saloon because of his Indian heritage, Falan Wilder, the man called Breed, severely wounds Reed Fowley, and then takes refuge in the desert. Fowley's father and brothers give chase, but are no match for Breed, who escapes and goes to his homestead in Lone Pine Canyon below the Mogollon Rim. But the Fowleys will not give up. They hire man-hunter Dutch Regan to find him. Once found, Reed Fowley, and brother Bud, hire Robert Candless, a former major of the Colorado Volunteers, and a band of savage outlaws to storm Breed's homestead and kill him. Breed, his wife-to-be Blessing, and his protege, Sparrow, must fight for their lives, or die.