They are the Earth's most revered protectors: Reed Richards, Susan Richards, Ben Grimm, and Johnny Storm -- the Fantastic Four. Celebrities around the globe and defenders of mankind, these extraordinary individuals have sworn to confront the perils and challenges facing the modern world and each other, always with unyielding courage, unerring wisdom, and an unshakable familial bond.

But their darkest hour may yet be at hand, as humanity's most frightening threat comes violently from beyond the stars...from the depths of the Negative Zone, a universe in a dimension parallel to our own -- one first discovered years ago by Reed Richards himself. And it is this terrifying and deadly menace that will ultimately test the measure and mettle of four heroes sworn to protect the human race at any cost -- even their own lives...