The United States is in the middle of a crucial presidential campaign when one of the two major candidates mysteriously disappears. Has he been kidnapped or killed? Only Denis Nayland Smith knows what evil force lies behind the crisis - the sinister genius of Fu Manchu - however even Sir Denis has not reckoned on the extent of his ambitions. Once a puppet candidate is installed in the White House the oriental fiend will be President Fu Manchu and the world will face its biggest danger yet.