Set in the beautiful wine country of Napa Valley, A Ton of Trouble has plus-size sleuth Josephine Fuller once again caught in the middle of a gruesome murder. When she receives a note from Wolf Lambert, the director of X-rated films starring XXL women, Josephine decides to stop and visit him at his winery. Her spur-of-the-moment impulse, however, leads her right into the middle of a murder investigation when a body is found in one of Wolf's wine barrels and her friend Thelma, a supersize porn queen, is one of the leading suspects.

Her investigation, however, has to take a backseat to her day job - looking into a women's clinic to see if it is a worthy cause for her wealthy boss to support. Josephine soon discovers that this women's clinic is a cover-up for extreme anti-abortionists. Unfortunately, it's headed up by a gun-toting, self-righteous religious woman who has taken an instant dislike to Josephine.

Soon Josephine is balancing her time between digging up the secrets of one of the most powerful wine families in the valley and uncovering what exactly is happening behind the closed doors of the clinic. As if that weren't enough, her on-again, off-again relationship with Mulligan seems to have turned back on. If only she can convince him that her involvement with the porn industry is a purely professional interest.