A rash of brutal killings - dubbed the "Machete Murders" by the press - have the people of New York living in fear. Assigned to the high-profile case are homicide detectives Sara Pezzini and her partner, Jake McCarthy, who soon find themselves neck-deep in trouble - not just from NYPD brass, but from voodoo priests, evil spirits, a brother and sister pair of hired killers, and a Goth band called The Mountains of Madness! Not exactly a normal homicide investigation, but then Sara is no ordinary cop - not when she's secretly the possessor of the Witchblade, a mystical weapon that can help her overcome her enemies - if it doesn't turn against her first....