Now that absent-minded Professor Brody has invented a serum that eliminates allergies to dogs, anyone can adopt a pup. But not if the cunning cats can help it. Led by Mr. Tinkles, a malevolent Persian with delusions of world domination, they wage a sneaky, sinister war against the professor and his family. It¹s not long before the dogs strike back by sending secret agents of their own to foil the feline plans. It¹s dogs against cats in the battle for the tummy-scratching affections of humans.