Spec-Ops First Sergeant Ellis Kirby leads a JSOC unit into the Tora Ghar cave system seeking WMDs, but finds something much worse. Infected by an ancient power summoned by an evil cleric Kirby and his companions are whisked back to secret military laboratories in the US. The plague of creatures - known as rakes - that is subsequently unleashed threatens to wipe out the entire population of the United States and perhaps the world. Through a country rapidly overwhelmed by the ravenous creatures, Kirby must fight for his life if he's to take the fight back to the monsters and their master. Across the same devastated landscape travel Bree and Jill Adams, sisters at odds, who must face their past to survive the future, and three misfits collectively known as the Ruby gang. Each must endure their travails before they are thrown together with Kirby, in a race to the eastern seaboard where the final conflict between man and beast is about to play out in a battle encompassing modern warfare and ancient magic.