In the deep mountains of Appalachia, the Flints of Leatherwood, Tennessee, spread the word of the gospels by handling deadly serpents and drinking lye in front of large gatherings of the faithful. Believing his ten-year-old son Jacob - called Toad or Spud - to be a prophet, Charles, the patriarch, takes the boy down a long and arduous path as they travel the back roads of the postwar Deep South in search of God and plumb the depths of their unorthodox brand of faith. But sudden, shocking tragedy will shatter Charles's cherished dream of building a ministry and a permanent church - and set young Jacob on a dramatically different course.