Meet Jimmy Neutron, boy genius and inventor extraordinaire! He bounces to school in a gravity bubble. His custom-built dog, Goddard, has more uses than a Swiss Army knife. And he navigates outer space in his homemade rocketship.

One night while Jimmy and his friends sneak out to the Retroland amusement park, his satellite is detected by evil Yokian aliens who kidnap all the grown-ups of Retroville! When Jimmy discovers what has happened, the kids blast off to rescue them! But will Jimmy and his friends find them before it's too late?