Big sister, Beezus, tries very hard to be patient with Ramona, but how many nine-year-olds have to put up with their embarrassing, annoying little sister? Sisters are supposed to love each other, but pesky Ramona doesn't seem very lovable to Beezus. The Trouble with Beezus and Ramonacontains the first four Beezus and Ramona books in one edition.